SELECTIONS.

W. Irving Hyslop, M. D., 4408 Chestnut St., West Philadelphia, Pa., says: "I have used Celerina quite largely, both in private and hospital practice, and with gratifying results. It is void of repugnant taste and is readily retained by the stomach. My experience with Celerina has been confined chiefly to its use in nervous diseases, particularly loss of nerve power, and the opium habit, in which conditions it has served me well, and I shall continue to prescribe it both in private and hospital practice."

Dysmenorrhea. "I have tried Dioviburnia in several obstinate cases of dysmenorrhea and it acted like a charm. I have since used it a great deal and find it satisfactory in all cases.”—I. F. Huff, M.D., Schnecksville, Pa.

Make a Note of This.—It is a matter of common observation that many cases of bronchitis will persist in spite of the continued, varied and judicious use of expectorants. "The cough," says one prominent physician, "hangs on, harasses the patient with its frequency and severity, and is exceedingly liable to recur every winter-to become a regular winter cough,' with its sequelae of emphysema, asthma and, ultimately, dilation of the right heart." Dr. Milner Fothergill, of London, insisted that cough of this character is due to lack of tone, not only in the general system, but in the blood vessels of the bronchioles. This authority demonstrated that the only successful method of treating this form of cough is by means of appropriate systemic and vascular tonic medication. It is particularly in this class of cases that Gray's Glycerine Tonic Comp. has gained a most enviable reputation. This remedy, which is a most palatable and agreeable one, not only has a selective tonic and anti-phlogistic action upon the respiratory mucous membrane, but it removes the ever-present element of systemic depression. The beneficial effects of Gray's Glycerine Tonic.Comp. even in rebellious cases are invariable and most pronounced.

Optimistic View for the Doctor.-If the doctor had never accomplished anything more definite in his life work than the relief of pain, than amelioration of human suffering, he would not have lived in vain. It is all very well to say that pain is physiological, that it is the cry of the nerve for more blood, yet its continuance cannot be borne by the patient, even by the most heroic Spartan. Long continued pain is dangerous, and while of course we never wish to

obtund and remove it so completely as not to be able to ascertain its cause, and remove the same, yet the best interest of our patient requires from time to time the administration of that which is opposed to pain. Remedies like opium, which relieve the pain and at the same time are exhilarating and alluring in their effects, are most ofttimes dangerous in the remote demoralization which they produce upon our patient. A remedy for the relief of pain which does not tie up the secrctions, which carries with it no exaltation, and no fascinations which tend in the direction of developing drug habits, is a desideratum. Five grain Antikamnia Tablets certainly meet this necessity. Antikamnia is also more prompt and decided in its action in labor than opium, and has none of the unpleasant after-effects. It may be continued in smaller doses to control afterpains, and rather favors than interferes with the secretion of milk. Where post partum hemorrhage is threatened it is always advisable to administer Antikamnia and Codeine Tablets, rapidly pushing their effects to therapeutic limit.

Cardiac Sclerosis.-At the Fifth French Congress of Internal Medicine, Professor Huchard (Die Heilkunde, October, 1899) made some very interesting remarks on the subject of cardiac sclerosis. He stated that if the proper treatment was resorted to in the early stages of the disease, a cure could often be effected. In this first stage, characterized by arterial hypertension, hygiene and diet are the two special therapeutic indications. The patient should take an abundace of milk, and avoid all stimulants, especially coffee, tea and alcoholic beverages, and also abstain from foods containing a large amount of toxins, as, for instance, fish, meats that are underdone or partially decomposed, preserves, cheese, sausage and game. The amount of fluids should be restricted in order not to produce artificial plethora and hypertension. On the other hand, diuretic drinks are advisable, since they promote the elimination of toxins. from the body. It is Huchard's custom to recommend his patients to take a glassful of Vittel, Evian, or Contrexeville mineral water, given with 8 grains of Lycetol, in the morning on an empty stomach and in the evening just before retiring.

Sanmetto as an Internal Remedy for Genito-Urinary Conditions."While fully realizing the superfluity of further testimonials concerning a remedy so well and favorably known to the entire medical profession as is Sanmetto, yet as I possess an extended knowledge of its reliability, based upon several years' clinical experience and on the treatment of hundreds of cases in which it has proven itself eminently fitted to lighten the cares of the genito-urinary surgeon, I am perhaps invested with a certain authority which should per

mit me the privilege of adding my meed of praise. In all the inflammatory conditions of the genito-urinary tract, from the meatus to the pelvis of the kidney, the administration of Sanmetto is invariably beneficial. It not only renders the urine bland and unirritating, but also exerts a specific action on the inflamed tissues, soothing and restoring the tonicity of the parts. Its tonic action on the prostate is of such a nature that it proves of equal advantage in cases of either hyperplasia or of atrophy, and there is no remedy so uniformly successful in the treatment of atonic impotency or presenility. I have found it of inestimable service in the preliminary preparation of cases requiring surgical interference, and, combined with salol, use it constantly to secure urinary anti-sepsis. I am fully of the opinion that Sanmetto represents all that could be hoped for or desired as an internal remedy for genito urinary conditions.” -H. R. Weber, M. D., Chicago, Ill.

Bromidia in the Treatment of Epilepsy.-The New Albany Medical Journal for November, 1898, contains an article on "Epilepsy Treated by the Use of Bromidia," by T. Edward Converse, M.D., of Louisville, Ky., which, after discussing the use of medicines. chiefly relied upon in the treatment of that disease, and giving the needful hygienic measures in considerable detail, concludes by referring to the question often raised: How long will the patient have to keep up the treatment?" If the bromides are given, they should be continued for at least two years after the last convulsion, or if combined with the chloral hydrate in the form of bromidia, a year and a half is sufficient in most cases. If the patient is having several attacks during the day, a teaspoonful of bromidia after the attack and repeated in an hour will abort the next attack, but, as a rule, one teaspoonful will be sufficient. Sanitarium, April, 1899.

Leucorrhea." Dioviburnia is nearly a specific in leucorrhea. The ingredients are all good; the combination better. I used it in a case of leucorrhea of long standing and it did good work. I do not think it will disappoint any practitioner. (I gave it in dessertspoonful doses.) I recommend it and shall continue its use. As the formula is given, physicians need not be afraid to try it, for it is no secret nostrum "-A. D. Brooks, M. D., Grand Island, N. Y.

Aseptic and Antiseptic.-These terms are in such every-day use that it would seem that the province of each must be clearly defined and well understood. We therefore felt that we must be in error when a prominent physician challenged our use of the term antiseptic, as applied to our collapsible tube container for Unguentine. We had thus described the office of this tube because, while not in

itself a germicide, it does exclude all septic germs and thus prevents contamination of its contents. There is practical agreement as to the meaning of Aseptic and but few consider it synonymous with Antiseptic. As to the latter term, however, there is a pretty even division into two camps, which may be called Antigermal and Germicidal. We quote a terse definition of each:

ANTIGERMAL. (a) Anything excluding sepsis is antiseptic. "Antisepsis is sometimes used simply as meaning the destruction or counteraction of sepsis as opposed to asepsis' in its proper sense. It realy means more-it means protection of aseptic substances from sepsis, as well as its destruction, and in this sense its application to a germ-proof container is correct."-Journal American Medical Association, Jan. 13, 1900; page 125. GERMICIDAL. — (a) Destruction of germs generally. "An antiseptic substance is one which is actively destructive to septic germs. For example, heat, electricity, and chemical germicides."-Medical Council, Feb., 1900.

(b) Destruction of germs only after infection has occurred. "Antisepsis implies a septic condition against which one directs chemical or other agents capable of correcting it. Asepsis has to do with those measures calculated to preserve a non-septic condition and may by accomplished by chemical or physical means." Western Clinical Recorder, Nov., 1899; page 399.

-THE NORWICH PHARMACAL COMPANY.

How to Vaccinate. This aseptic vaccine is prepared in our biologic laboratory, under the direct supervision of Chas. T. McClintock, M. D., and E. M. Houghton, Ph.C., M. D., with a corps of trained assistants. The purity of the vaccine is assured by the most rigid antiseptic and aseptic measures. The heifers before being vaccinated are examined by our veterinary surgeon and tested with tuberculin; if any evidences of disease are found the animal is rejected. The pulp of cowpox vesicles is mixed with pure glycerin for the destruction of the comparatively few bacteria likely to be present despite the most careful manipulation of the vaccine-producing animal. Moreover, the glycerin is perfectly harmless when applied to the abraded skin in connection with the prophylactic use of the vaccine. Glycerinated vaccine has been extensively employed. upon the continent of Europe and in many American cities, notably New York and Chicago, and wherever employed has proven far superior to the old style "points."

A number of methods have been used in vaccinating-the following being one of the simplest and most successful: Cleanse the site of inoculation with soap and water, and carefully dry. (Do not use bichloride solution, carbolic acid, or any other disinfectant,

unless there are special reasons for doing so-in which case all traces of such disinfectant should be removed with sterilized water before vaccinating.) Take the small rubber bulb in the left hand, with the neck of the bulb pointing to the left. One of the sealed glass tubes, held in the right hand, is inserted into the opening in the top or rounded end of the bulb, and, with a slight rotary motion, pushing through until the bulb is impaled and resting at about the center of the tube. The end of the tube to the right is then broken off and the tube pushed on through until the open end is well within the cavity of the bulb. Now break off the other end of the tube, and lay the tube aside until the site is scarified. Scarify a single small area—say about one-quarter or one-third of an inch in diameter-using for this purpose almost any sterile steel instrument, such as a needle, scalpel, or one of the many instruments especially designed for this work. To apply the vaccine, hold the bulb between the thumb and second finger, the tip of the index finger covering the air-hole at the top, when slight pressure upon the bulb will force the vacine out upon the scarified area. The vaccine should then be rubbed in thoroughly with the flat side of the instrument, with an occasional slight scratching or pricking with the point, in order to facilitate penetration and adsorption. Ample time should be given for the lymph to dry, and the clothing should never be replaced until the site presents a glazed or varnished appearance. No dressing is required except in cases where very rough or dirty under-garments are worn, and then a piece of clean, soft linen or cotton is the most suitable.

1. Don't prepare the site by washing with antiseptic solutions. Or, if this is thought necessary- 2. Don't fail to rinse thoroughly with sterilized (boiled) water, and dry. 3. Don't draw blood if you can help it. A gentle oozing of serum gives much better results. 4. Don't fail to rub the vaccine thoroughly and persistently into the abrasion. 5. Don't replace the clothing until the vaccine is thoroughly dry. 6. Don't apply antiseptic dressings. (Many of our most successful vaccinators never use any dressing except in cases where there is danger of infection from the environment or uncleanliness of the patient.) 7. Don't expose vaccine to extremes of temperature. High temperatures spoil it. 8. Don't expect to find a swollen arm, indurated glands, high fever and a suppurating ulcer -these belong to the old-fashioned means and methods of vaccinating. 9. Don't accept the word of the patient or parent as to the success or failure of the process. Examine the case yourself, and if you find a typical vesicle-or the remains of one or more that may have been ruptured and emptied-assure the patient that he is protected against smallpox. 10. Don't be in a hurry about passing judgment upon a "take." Sometimes the vesicles are delayed in their development.