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the following two cases it will be noted that one was much more severe than the other and did not yield as readily:

Case I-Miss L, a well developed and well-nourished blonde of 16, applied to me for the treatment of quite a large tumor of the left side of the neck, situated at the border of the ramus of the jaw and extending down some three inches. In its horizontal diameter the tumor measured about four inches, and was more or less nodulated and nearly two inches through. It had been some time in growing, and the physician in her town called it scrofulous and proposed excising it. As she refused this method she was referred to me for advice. Upon examination of the family history, the anamnesis, and direct examination of the tumor, tuberculosis as a possible cause was rejected. A drop of blood under examination showed the trouble to be pseudo-leukemia. Acting upon this, the treatment ordered consisted of the following: R-Iodo-bromid calcii co. (Tilden), 3xvi. Sig. A teaspoonful in water four times a day.

In addition to this the patient was ordered to rub in well the following ointment: R-Tinct. iodini co; 3j, Ung. aquæ, rosæ 3j. M. Sig. Rub in twice daily.

After two weeks of this treatment a perceptible diminution in the size of the tumor could be made out on mere inspection. The treatment was continued, and in about two months there was no vestige left of the tumor which had existed. An examination of the blood showed it to be normal. To-day, after a lapse of over three years, she continues healthy, and there has not been the slightest indication of a return of the trouble.

Case II.-Mr. R- a man, already past 50, consulted me in regard to a trouble which had annoyed him for quite some time. He complained of a large number of varied symptoms, which were all referable to one cause. He had enormously enlarged lymphatic glands in the groins, which were so interwoven that they presented one large mass on either side. Enlarged as well as indurated glandular masses existed in the axillæ, upon both sides of the neck and along the right sterno-cleido mastoid muscles. Much complaint was made of an "asthma" which annoyed the patient very much. The condition was determined to be pseudo-leukemia and the difficulty in breathing caused by the lymphatic tumors in the chest cavity. Acting upon these findings the following was ordered: R-Iodo-bromid. calcii co. (Tilden), 3xvj. Sig. Two teaspoonfulls in water four times daily.

For external use the following ointment was ordered applied to the enlarged masses twice daily: R-Tinct. iodini co, Ziiss; Ung. aquæ rosæ, 3ij. M. Sig. Apply thoroughly twice a day.

In a very short time the glandular masses softened. In a few weeks respiration became easier and soon thereafter it was normal. The patient complained of weakness and was given Vin Mariani, which aided him considerably. In order to accentuate the action of the remedy he was taking he was given arsenauro in ten-drop doses after each meal. At last accounts he was doing well. Were examples of pseudo-leukemia more numerous, a line of treatment might be formulated which perhaps might prove specific. This not being available at present and knowing well the good effects of iodo-bromide of calcium upon the lymphatic glandular structures, I employed it with the good results recorded above. It is a safe and a reliable remedy and its worth and value have been fully demonstrated in a large number of conditions which require an alterative of undoubted strength and virtue.

The two cases which have been outlined above are such as to suggest the possible value of this remedy in tubercular glands. It is well worthy of a trial, as it seems to have an elective affinity for lymphatic glands, and by its action upon them may so act upon the tubercle bacilli as to render them innocuous, if it cannot destroy them. In one case of strumous glands of the neck in a girl, which the writer treated, it acted well, although it required some considerable time to effect a cure, which seemed absolute, although it might only have been apparent. For six years there was no return. -St. Louis Medical and Surgical Journal, April, 1900.

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Editorial Items.—Continued.

Chloretone.

What is Chloretone? We are asked this question almost every day. It is a new hypnotic and anesthetic. The literature on the subject is very plentiful. Chloretone is probably one of the most valuable drugs of its kind that has been put upon the market within the last year.

Migraine. Hirtz states that 4 grains each of caffeine and sodium benzoate often act very well, repeating the dose if need be every two hours until four doses have been taken. Graeme Hammond recommends 11⁄2 grains each of methylene blue and powdered nutmeg in capsule four times a day.

Ptomaine Poisoning.--The oyster and the syrimp are natural scavengers and hence should be raised only in pure, ocean-free waters. Neglect of this fact, says the editor of the Pacific Medical Journal, has caused quite an endemic of ptomaine poisoning in San Francisco during the last year or two.

An Itching Ear.-Alex W. Stirling writes to the Laryngoscope that itching of the auditory meatus is often due to irritation arising near the pharyngeal mouth of the Eustachian tube, and transferred to the ear. It follows that treatment, to have a permanently good effect, must be directed to the pharynx as well as the ear.

Scarlatinal Desquamation.-Williams (Medical News) says that the process can be shortened by three or more days by means of regular inunctions all over the body (except the scalp) with a mixture of 1 part glycerin and 9 parts 15-volume hydrogen peroxide, acidulated with 1 per cent. hydrochloric acid.

Method of Obtaining the Sputum of Infants.-Meunier (quoted in Progressive Medicine) recommends that simple lavage of the stomach should be practiced in young children early in the morning, shortly after the fit of coughing that commonly occurs on waking. The sputum thus obtained can be readily examined for pus and tubercle bacilli.

Chronic Endarteritis.-W. H. Thompson (Medical Record) has found mercuric chloride, 1-24 grain, three times a day for a week, very efficacious in the treatment of this condition. When chronic enlargement of the heart accompanies the arterial disease, he prescribes 5 grains of sodium iodide three times a day for weeks or months.

Peroxide of Hydrogen in Uterine Hemorrhage.-Platon (quoted in New York Medical Journal) has used uterine injections of a dram of this drug in two cases with marked success. The first case was ⚫one of gonorrheal hemorrhagic metritis; the second, an obstinate and apparently causeless metrorrhagia in a very stout patient near the menopause.

The Essentials of Hematology.-The enterprising Palisade Manufacturing Company, makers of Hemaboloids, have issued the first of a proposed practical series, complimentary to physicians, upon the subject above named. It is a practical guide to the clinical examination of the blood for diagnostic purposes, and is illustrated with six colored plates.

Normal Saline Injections in Typhoid Fever.-In cases associated with much emaciation, Hare (Therapeutic Gazette) strongly recommends subcutaneous normal salt injections, as not only replacing the lost fluids of the tissues, but also tending to supply the kidneys. with such a quanitity of liquid that they can readily pass out of the body impurities which should be eliminated.

Sparteine in Fatty Heart.-In true fatty degeneration, Pliquet (International Medical Annual) extols the value of spartein, especially because of its long-sustained influence upon the heart. It may be given by the mouth in doses of 20 to 30 drops of a 1 per cent. solution, thrice daily, or in pills, 2-5 grain extract of spartein with 3-5 grain extract of cinchona; two to four pills a day.

Normal Prophylactic Appendectomy.-The Medical Review of March 17 contains a symposium on the advisability of the removal of the healthy appendix in children as a prophylactic measure. Nearly a hundred representative American surgeons give their opinions, which so far as we have noted seems to be all but unanimously against the advisability and justifiability of such a procedure.

Treatment of Coughs.-We select the following practical points from the International Medical Annual: Reflex coughs, require bromides and valerian or strychnine. Coughs in gouty cases, with congested uvula and pharynx, are best met by salicylate of soda and lithium salts. If due to laryngitis, avoid talking and use inhalations of cocaine or benzoin or a spray of 10 per cent. menthol in fluid vaselin. Counter-irritation over sternum by a blister or mnstard leaf is of service. A useful linctus is made of equal parts oxymel of squills, compound tincture of camphor and syrup of tolu: a teaspoonful every three or four hours. Antikamnia and codeine, in 5-grain tablets every hour, often relieve irritable cough.

The Cardinal Pathognomonic Sign of Fracture of the Lower End of the Radius. According to Martin W. Ware, (Medical Record, March 31) who speaks from an experience of 300 cases, this sign of Colles fracture consists in the altered relation of the ulnar and radial styloids the latter being normally at a lower level than the former. The classical silver-fork deformity, he says, occurred in not more than 10 per cent. of his cases.

Xiphoid Rheumatism.-Hirtz and Roustan (International Medical Annual) draw attention to rheumatic inflammation of the sternoxiphoid articulation, which may be the only joint affected. The symptoms comprise dyspnea and severe epigastric pain, much increased by pressure over the lower part of the sternum. There may be local swelling. The uuthors recommend the use of a blister externally; salicylates internally.

Chronic Villous Polyarthritis.-Schueller (quoted in Medical Record) states that this affection often develops spontaneously, and more likely depends upon disturbance of nutrition than upon bacterial infection. Most of the patients suffer from constipation and flatulence and subelimination of lime salts. The dietary ought, therefore, to be poor in this particular element, and special attention should be paid to the emunctories.

The Test of Time and Experience. This is the title of a neat little brochure recently issued by Mr. Fellows. It explains briefly the nature and effects of the hypophosphite salts, as combined in the syrup known as Fellow's Hypophosphites, and their special application in this form to those cases of disease which do not yield readily to ordinary treatment. Special consideration is given to diseases. of the respiratory organs, for which this medicinal combination has been found most beneficial.

Almond Bread. The following receipt for this diabetic food is furnished by Kleen: The powder of one-quarter pound dried and finely pulverized almonds is put in a linen bag and cooked a quarter of an hour in water, with some drops of vinegar; then well kneaded with 31⁄2 ounces of butter and two whole eggs. Then the yolks of three other eggs and some salt are added to the mass. The whites of the three eggs are well beaten and also added, whereupon the whole is put in a butter form and baked.

Bremer's Test for Gylcosuria.-Dr. Ludwig Bremer has modified his color blood test so as to make it applicable to the urine in cases of suspected diabetes. The method consists in dropping a small portion of a powder composed of 3 parts gentian-violet and 2 parts

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