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PEPTO-MANGAN.-"In reply to your favor of the 8th inst., I have the honor to inform you that your Pepto-Mangan (Gude) has been employed with much success, and that it is frequently prescribed here."-B. B. Edler v. Wehrenalp, Teesdorf, Austria.

PONCA COMPOUND.-"The sample of Ponca Compound which you were kind enough to send me, gave such satisfaction that I have continued to prescribe it in the class of cases for which I first used it, namely, chronic metritis. I have also secured satisfactory results from its use in ovarian neuralgia as well as in inflammations involving those organs.”—Wm. E. Robins, M. D., Washington, D. C.

BROMIDIA.—"I have used Bromidia in cases of insomnia, restlessness and threatened convulsions, with surprising results, finding that a dose of from 15 drops to 1 drachm to be sufficient according to age and how often to be repeated. I have combined Bromidia with Papine where I wished to annul pain with excessive nervousness, the combination acting very happily also in bladder troubles. I use Bromidia and Papine very much in my family."-Chas. E. Quetil, M. D., Philadelphia, Pa.

DYSENTERY AND FLATULENCE.-The griping pain and flatulence which accompany bowel and stomach complaints, particularly during the heated term, are so readily overcome and controlled by the timely administration of one or two Antikamnia & Salol Tablets, repeated every two or three hours, that it behooves us to call our readers' attention to the grand efficacy of this well-known remedy in these conditions. The above doses are, of course, those for adults. Children should be given onefourth tablet for each five years of their age. When the attack is very severe, or when the disturbance is evidenced at or near the time of the menstrual period, we find it preferable to give two Antikamnia & Codeine Tablets, alternately with the Antikamnia & Salol Tablets. The latter tablets promptly arrest excessive fermentation and have a pronounced sedative effect on the mucous membranes of the bowels and stomach, and will check the various diarrheas without any untoward effect.

SENG. "I regard Seng as one of the best, if not the best remedy that I have ever had experience with in all dyspeptic and gastric troubles. I have been practicing thirty-five years, and thus you will see this is saying much for a remedy. Its action is slow, but I deem this all the better."-D. W. Tice, M. D., Troy, Mo.

SEASONABLE SUGGESTION.-Digestive disturbances SO prevalent at this season and followed by diarrhea, cholera morbus and cholera infantum, demand prompt attention and treatment. Hayden's Viburnum Compound (genuine), administered in drachm doses in hot water, not only corrects the existing condition, but is a pronounced antispasmodic and relieves the severe pain always accompanying these cases.

PRURITUS VULVAE.-Pruritis vulvæ may be due to a variety of causes, both of local and constitutional origin. Probably the most common is a vaginitis or vulvitis, giving rise to irritation of the nerve filaments, which are laid bare by the desquamation of the epithelium over the inflamed area. In this form of pruritus the immediate indication in the treatment is to reduce the discharge, which is the primary cause of the distressing itching, and to render is as unirritating as possible by preventing its decomposition. This can be readily done by the use of the Micajah's Medicated Uterine Wafer, which is at the same time astringent, antiseptic and alterative. At the beginning it will be best to dissolve a wafer in about a pint of water and use it as an injection. Later as the irritation subsides, the wafer itself may be inserted every third day. It is always advisable to precede its use by a copious douche of hot water.

BLOOD FOR BABIES.-In the course of the second year there comes a time when the milk diet begins to be insufficient for the growing child, and nature calls for a change, while yet the system is in many cases unprepared for solid food. This kind of deadlock results in diarrhea or constipation, anæmia, restlessness, fretfulness, etc. In such cases the fit and radical remedy will be found in the administration of say ten drops of bovinine in a little milk, at intervals of three hours. Little Robert Valverdie, a patient who came under my care in the condition of malnutrition. above described (after trying all the usual medical helps with no benefit), was immediately restored by the direct blood treat

On the second day of taking bovinine, the constipation

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and other trouble began to be relieved, and on the third day all signs of ill health had disappeared as if by magic. This simple treatment was continued for three weeks, the child thriving beautifully. Case reported by Dr. T. J. Riggs.-Bovinine Co.

ECZEMA. "I have used Germiletum on a very stubbornr case of eczema (hands and face) and glad to say with perfect satisfaction; a decided improvement in twenty-four hours. Have since prescribed it in a case of eczema capitis, girl of 12 years, with same happy results."-C. C. Gentry, M. D., Webb City, Mo. The Dios Chemical Co., St. Louis, Mo., will furnish fullsize (14 oz.) bottle of Germiletum, free, to physicians who have not already received same, they paying express charges.

THE PREVENTIVE AND CURATIVE TREATMENT OF HAY FEVER. It is difficult to conceive of a more miserable creature in all the world than the hay fever sufferer. The attack not only makes him exceedingly uncomfortable, but renders him unfit for business or the pleasures of society. Aside from the annoying and continual discharge from the nostrils, the eyes are suffused, the secretion of tears is increased, the nasal passages are obstructed, and an intense burning sensation is experienced; the latter is not entirely limited to the mucous membranes, but not infrequently involves the cutaneous surfaces of the forehead, cheeks and nose. Violent attacks of sneezing occur, which are so prolonged, at times, as to completely exhaust the sufferer and bring on severe headache. The condition is one of utter wretchedness, and there is extreme malaise, amounting occasionally to complete prostration. The lightest duties become irksome tasks, and many an active, industrious and useful member of society is completely incapacitated while "the season" lasts.

For years some convenient means of relief has been sought. Change of scene does very well for those, unfettered by business, who can afford to travel. But to many very worthy people a change of scene is out of the question. Naturally the greater number of the afflicted are accustomed to look to the medical profession for the help they need. But what has the medical profession actually accomplished for the permanent relief of the sufferer or the cure of his ailment? There is scarcely a sedative, astringent, tonic, nervine, or alterative drug in the materia medica, that has not enjoyed an evanescent reputation as a useful remedy in the treatment of hay fever. Until the discovery of Adrenalin,

each had been as much of a disappointment as its predecessor, and none had afforded more than the merest temporary relief.

There is increasing evidence that Adrenalin fully meets the indications as a remedial agent in hay fever. It controls the nasal discharge, allays congestion of the mucous membranes, and in that manner reduces the swelling of the turbinal tissues. As the nasal obstruction disappears, natural breathing is materially aided and the ungovernable desire to sneeze is mitigated. In short, a season of comparative comfort takes the place of the former condition of distress and unrest. Adrenalin blanches the mucous membrane by vigorously contracting the capillaries, and thus reduces local turgescence. It strengthens the heart and overcomes the sense of malaise, so frequently a prominent feature in cases of long standing.

In the treatment of hay fever the Solution of Adrenalin Chloride should be used. This preparation is supplied in the strength of one part Adrenalin Chloride to one thousand parts Normal Saline Solution, and is preserved by the addition of 0.5 per cent. Chloretone. The 1-1000 solution should be diluted by the addition of four parts Normal Salt Solution, and sprayed into the nares with a "Cocaine" atomizer. In the office, the 1-1000 solution may be applied in full strength. A small pledget of cotton is wrapped about the end of an applicator and moistened with a few drops of the solution (1-1000). The speculum is then introduced, the patient's head is tilted backward in a position most favorable for thorough illumination by the head mirror, and the visible portions of the lower and middle turbinate bodies, and the septum, are carefully and thoroughly brushed. The same application is made to the other nostril, when usually relief follows in a few moments. Should the benefit prove only partial, the 1-5000 solution may now be sprayed into both nares, and a few drops instilled into both eyes. The effect of this treatment may be expected to last for several hours. Indeed, some physicians report that it is necessary to make but one thorough application daily to afford complete relief.

It is also recommended that Solution Adrenalin Chloride be administered internally in 5 to 10-drop doses, beginning ten days to two weeks prior to the expected attack. In explanation of the beneficial effect of the drug when used in this manner, the suggestion has been made that hay fever is essentially a neurosis, characterized by a local vaso-motor paralysis, affecting the blood supply of the eyes, nose, face and pharynx, and occasionally of the laryngeal and bronchial mucous membranes. Adrenalin overcomes this condition, restores the normal balance in the local blood pressure, and thus aids in bringing about a cure. The profession is to be congratulated that it has at last an agent that, if not a specific, fulfills the therapeutic indications more completely and with greater satisfaction than any other remedial measure recorded in the history of medicine.

Editorial Items-Continued.

Whey in Typhoid Fever.-A. T. Bridham (Lancet; Medical News) reviews a series of seventy-three cases with a deathrate of 2.7 per cent. In these cases whey was used as a partial or complete substitute for milk, over which it has the very great advantage of not forming decomposing curds.

Prostatic Congestion.-Stordeur (J. A. M. A.) recommends the following suppository: Potassium iodide, 5 grains; ichthyol, 3 grains; morphine hydrochlorate, 1-6 grain; extract of datura, 1-6 grain; and sufficient cocoa butter to make one suppository, one or two of which may be used daily.

Tapping the Chest.-In tapping the chest (International Journal of Surgery) it is well to remember that a line drawn horizontally from the nipple around the chest passes over the sixth intercostal space midway between the sternum and the spine. This rule may prove serviceable in stout people in whom it is difficult to count the ribs.

Human and Bovine Tuberculosis.-After ten years' experimentation, Behring affirms that human and bovine tubercle bacilli are identical. Ravenel lately obtained from the mesenteric gland of a child, which had died from tuberculous meningitis following primary intestinal tuberculosis, a culture of tubercle bacilli which were intensely virulent to cattle.

Chronic Sciatica.-After the trouble has become chronic and all acute signs of inflammation have disappeared, Harrison1 Mettler (Therapeutic Gazette) resorts to the steady use of strychnine, preferably by the subcutaneous method, as recommended by Leyden, in doses of from 1-70 to 1-20 grain twice a day. Massage, baths, and mild currents of electricity should be used every day.

For Feeble Uterine Contractions in Second Stage of Labor. -Simon Marx (Medical Critic) employs sugar as a muscular stimulant, giving the patient several lumps to eat. The method has a physiologic basis, and he claims is successful to a certain degree. Quinine, 10 grains of the muriate by mouth or rectum, is of great value in spurring on flagging pains during the first

stage.

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