The classification of different forms of cancer if properly carried out, might lead to the elimination of some forms which may be found to be due to special parasites (as for example, actinomycosis has been eliminated), and to the separating off of what may be found to be special types, or only seeming cancer. In all investigations of this nature full and detailed histological, chemical, bacterial, or other parasitic investigations must be made and a full history of each case clinically recorded. The reputed transplantation of cancer into wound margins ought to be specially enquired into, with a view to the important bearing such an occurrence would have on other transplantation experiments. Such transplantation experiments should only be carried out with regard to the special species of animal in which the original growth occurred, and the special tissue in which it seemed to have had its origin. For all experiments of this nature the importance of the assistance of a trained veterinary man is very evident, for it would be. especially necessary to exclude the possibility of previous infection. A systematic study of the effects of persistent irritation of different epithelial surfaces in different species of animals might be found to have important bearings. In this category possibly the study of "Petroleum cancer" and "Sweeps' cancer" might be placed. Those engaged in post-mortem examinations should be encouraged to search systematically for, and record all evidence of incipient or undetected malignant disease. Such an investigation might throw much light on the internal conditions, e. g., in the alimentary canal, which in themselves may perhaps lie long dormant, and in the end become malignant, in the same way as other conditions on the surface of the body are known to do. A comparative study of mitosis and vegetative activity would require to be undertaken. Such an investigation would cover not only mitotic and vegetative activity in embryonic and cancer cells, but also that occurring in the cells of benign tumours, and of tissues which have reverted to an embryonic type in processes of repair, and with consideration of that over-production which is an essential feature of repair. I would respectively submit that any such scheme as the foregoing can only be provisional, and has been drawn up in full consciousness of the difference between drawing up a scheme on paper and putting the same into practice. I do not claim that this hastily drawn up scheme is adequate to cover the whole field of enquiry. In conclusion I would point out that the investigation must necessarily follow the lines which accumulated experience will dictate. Edinburgh, October 24th, 1902. (Signed) E. F. BASHFORD. INDEX. Accuracy in dosage, 364. type of growth, 86, 187. Adaptability and biological altera- intestine in fowls, 45. Adenoma of the liver of mouse, 72. of the lung in mice, 73, 76, 78, -, sebaceous, 74, 76. of the skin of the frog, mul- Adenomatous areas, association of structure of a lymphatic glan- structure, reversion of alveolar tumours in the frog, bilateral, Age-incidence of carcinoma and sar- coma, 6. Age, influence of, 285, 317, 325. Albrecht, E., 108. Albrecht, H., 199. Alleged increase of cancer, 8, 16. Alteration of sarcoma cells, progres- Alternating phases of increased and diminished energy of growth, phases in tumour-cells, nature - phases of keratinised epithelium Amphiaster, 64. Amphibian, urodele, 50. Amphibians, cancer in, 47. ANALYSIS OF GROWTH OF CANCER, EX- of stomach contents, man, of stomach contents, mice, Anaplasia, 89, 169, 172, 173. Animals, young, more suitable for propagation of cancer, 265. Auti-bodies in the serum, presence Anus, epithelioma of, in a female Apolant, 70, 76, 77, 86, 104, 108, Appearances of degeneration, histo- of grafts, naked-eye, 343. Ara macao, 45. Areas, light and dark, in Jensen's Arsenic cancer, 22. Artery, emboli in the pulmonary, 70, 91 96, 100. Artificial purification of mixed tumours, attempts at, 206. of chronic irritation with the Asymmetrical mitosis, 63, 66. 319, 386. Atrophic changes of carcinomatous alveoli in sclerotic tissue, 213. mixed tumours, 206. Australia, Central, 27. Avidity for food material, differential, 108, 111, 112, 116. |