Scientific Reports on the Investigations of the Cancer Research Fund, Volume 3Taylor & Francis, 1908 |
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Page xxii
... doses , weights of tumours and of animals , statements of age , of time , number of animals inoculated as well as of ... dose of a drug was determined for the first time by Fraser between 1863 and 1868 for Physostigma venenosum and its ...
... doses , weights of tumours and of animals , statements of age , of time , number of animals inoculated as well as of ... dose of a drug was determined for the first time by Fraser between 1863 and 1868 for Physostigma venenosum and its ...
Page xxiii
... dose of morphine the basis of his arguments . At Fraser's instigation I was able to prove , after determining the minimal lethal doses of the two drugs , that atropine did abolish the lethal action of morphine , and to show that the ...
... dose of morphine the basis of his arguments . At Fraser's instigation I was able to prove , after determining the minimal lethal doses of the two drugs , that atropine did abolish the lethal action of morphine , and to show that the ...
Page xxiv
... dose largely determines the size and weight the resulting tumour will reach in a given time . Its size may vary directly or inversely with the dose , according to differences between different tumours , and between the cells of one and ...
... dose largely determines the size and weight the resulting tumour will reach in a given time . Its size may vary directly or inversely with the dose , according to differences between different tumours , and between the cells of one and ...
Page 103
... doses of tumour material ( 0.1 to 0-2 gr . ) are introduced into each animal than in our procedure ( 0.01 to 0.02 gr . ) . The amount of mechanical injury to the parenchyma involved in this method is also of importance . As a ...
... doses of tumour material ( 0.1 to 0-2 gr . ) are introduced into each animal than in our procedure ( 0.01 to 0.02 gr . ) . The amount of mechanical injury to the parenchyma involved in this method is also of importance . As a ...
Page 112
... dose had attained the size of that which initiates the growth with a large dose , the weights of animals and tumours in the two groups should exhibit a parallel behaviour . It is only in the case of different strains of transplantable ...
... dose had attained the size of that which initiates the growth with a large dose , the weights of animals and tumours in the two groups should exhibit a parallel behaviour . It is only in the case of different strains of transplantable ...
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Common terms and phrases
acini acinous adeno-carcinoma adenoma adenomatous alveolar alveoli Apolant appearance Average weight axilla biological blood Cancer Research Fund carc cent chromosomes connective tissue degeneration dose E. F. BASHFORD early stages Ehrlich emulsion energy of growth epithelial epithelium examined experimental experiments fibroblasts gland glycogen graft grms growing tumours Haaland Hæm hæmorrhagic tumours histological host hydrochloric acid Ibidem Imboden immunity Imperial Cancer Research implantation infiltration inoculation investigation J. R. Ford Jensen's tumour keratinisation Krebsforschung large number lungs malignant new growths mamma mammæ mammary material metastases Microphoto mitoses mixed tumours mouse tumours necrosis necrotic nodules normal animals normal mice observations obtained occurred operation parenchyma percentage of success Period of Digestion peripheral primary tumour proliferation propagation rats re-inoculation reaction recorded resistance sarcoma development sarcomatous change sclerotic skin spindle-cell spontaneous absorption spontaneous tumours squamous-celled carcinoma Stomachs strains stroma transplanted tumours tumour 27 tumour 32 tumour cells tumours developed zoological distribution
Popular passages
Page 334 - The phagocytosis of formed cellular elements plays an important role in inducing resistance ; serum is impotent to produce resistance, blood corpuscles do so. The energetic phagocytosis which accompanies the spontaneous absorption of transplanted tumours, and which occurs in absorption after exposure to radium, speaks strongly for the conclusion that the processes are the same in kind when blood or tumour cells, being absorbed, produce resistance. But we are as yet unable to determine the extent...
Page 312 - Preliminary communication regarding an immune body capable of inhibiting the development of cancer in mice (adeno-carminoma, Jensen).
Page 22 - ... cancer, its apparent greater frequency in some geographical areas (whether large or small) than others, the presumable importance of race, diet, soil, climate, are all problems of much less importance than the infective or non-infective nature of cancer ; but we must not lose sight of the fact that it is in all probability as much without the province of statistics to supply the direct answer to the question, What is the cause of cancer ? as it was for statistics to directly prove the causes...
Page 312 - A study of the influence exerted by a variety of physical and chemical forces on the virulence of carcinoma in mice. By GHA Clowes, Ph.D. Evidences that infected cages are the source of spontaneous cancer developing among small caged animals.
Page 3 - I cannot refrain from pointing out that the number of deaths assigned to cancer increases from one country to another in a manner parallel with the increasing accuracy of the vital statistics of the several countries.
Page 21 - ... must remain indispensable so long as we are unable to test the relative importance of each. The relative importance of some of these circumstances can only be finally cleared up after the true nature of cancer has been ascertained, and the purely statistical investigation of the incidence of cancer will remain more or less empirical until this end is attained. The statistical investigation of infective diseases was pursued empirically before the developments of bacteriology directly demonstrated...
Page 21 - ... statisticians make of the available data. Until we shall be able to start cancerous proliferation in a tissue at will, we shall remain in this same unfavourable position for determining the true importance of many circumstances, which at the same time it is unjustifiable to ignore. The increased number of deaths recorded from cancer, its apparent greater frequency in some geographical areas (whether large or small) than others, the presumable importance of race, diet, soil, climate, are all problems...
Page 5 - ... whooping-cough and suicide." In briefly summarising the impression made by a study of the death-rates from cancer in European countries, I may state that comparisons between different countries, with a view to establishing differences in the absolute incidence of cancer, appear to me to be entirely fallacious. The dimensions of the differences are not so great that they are incapable of explanation by (1) the varying difficulties in the way of obtaining accurate records of the numbers of deaths...
Page 5 - ... statistics, new growths are grouped together, in a more indiscriminate fashion, eg, in Switzerland, for males, all fatal diseases of the prostate gland are grouped under the heading of " cancer " of that organ. The factor introducing most disturbance into the number and the value of the data is probably the manner in which the certification of deaths is effected, and the extent to which this is solely the duty of medical men, as in some States, or merely the ignorant opinion of a layman, after...