Pediatrics, Volume 2

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Pediatric Publishing Company, 1896
 

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Page xi - BABY POWDER." The " Hygienic Dermal Powder " for Infants and Adults. Originally investigated and its therapeutic properties discovered in the year 1868 by Dr. Fehr, and introduced to the Medical and the Pharmaceutical Professions in the year 1873.
Page 119 - ... units for the first injection, to be repeated in from eighteen to twenty-four hours if there is no improvement ; a third dose after a similar interval if necessary. For severe cases in children under two years...
Page 100 - Behring's original claim, that if cases were injected on the first or second day the mortality would not be 5 per cent., is more than substantiated by these figures. The good results obtained in third-day injections were a great surprise to your Committee. But after three days have passed the mortality rises rapidly, and does not differ materially from ordinary diphtheria statistics. Our figures emphasize the statement so often made, that relatively little benefit is seen from antitoxin after three...
Page 118 - ... laryngeal cases (membranous croup.) In one-half of these recovery took place without operation, in a large proportion of which the symptoms of stenosis were severe. Of the 533 cases in which intubation was performed the mortality was 25.9 per cent., or less than half as great as has ever been reported by any other method of treatment.
Page 117 - SUMMARY. 1. The report includes returns from 615 physicians. Of this number more than 600 have pronounced themselves as strongly in favor of the serum treatment, the great majority being enthusiastic in its advocacy. 2. The cases included have been drawn from localities widely separated from each other, so that any peculiarity of local conditions to which might be ascribed the favorable reports must be excluded. 3. The report includes the record of every case returned except those in which the evidence...
Page 100 - Of the 4,120 cases injected during the first three days there were 303 deaths — a mortality of 7.3 per cent., including every case returned. If from these we deduct the cases which were moribund at the time of injection, or which died within twentyfour hours, we have 4,013 cases, with a mortality of 4.8 per cent. Behring's original claim, that if...
Page 119 - ... units, to be repeated as above if necessary ; a second dose is not usually required. The dosage should always be estimated in antitoxin units and not of the amount of serum. (2) Quality of Antitoxin. The most concentrated strength of an absolutely reliable preparation. (3) Time of Administration. Antitoxin should be administered as early as possible on a clinical diagnosis, not waiting for a bacteriological culture. However late the first observation is made, an injection should be given unless...
Page 108 - Operations were done in 565 cases, or in 16.7 per cent, of the entire number reported. Intubation was performed 533 times with 138 deaths, or a mortality of 25.9 per cent. In the above are included nine cases in which a secondary tracheotomy was done, with seven deaths. In thirty-two tracheotomy only was done with twelve deaths, a mortality of 37.4 per cent. Of the 565 operative cases, sixty-six were either moribund at the time of operation, or died within twenty-four hours after injection.
Page 108 - In establishing the value of the serum, nothing has been so convincing as the ability of antitoxin, properly administered, to check the rapid spreading of membrane downward in the respiratory tract, as is attested by the observations of more than 350 physicians who have sent in reports.
Page 522 - ... an emetic of sulphate of zinc. The fluid easily passes the obstruction, and is, of course, rapidly coagulated in the stomach into a more or less solid mass, which, on being ejected, forces the obstruction before it, and so effects its removal.

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