Depression and Dementia: Progress in Brain Research, Clinical Applications, and Future TrendsNova Publishers, 2005 - 349 pages Many of the mechanisms of brain action, in health, as well as diseases like depression and dementia, are non-linear. The psychomotor theory can shed some light on the brain-mind-body interaction in health and disease. Specific neurotransmitters through their different receptor subtypes ultimately act along some final common pathway, in a lateralised fashion to produce depression and dementia. The currently available neurochemical and genetic evidences and their correlation with life events from population based studies, may be useful in screening susceptibility to dementia and depression. Further, criteria may be set up for susceptibility to these diseases and they might help designing early interventions in prevention of depression and dementia. The breakdown of the BBB (Blood brain barrier) through Heat Shock Protein (HSP) is also responsible for many neurodegenerative diseases. Aggressive and individualised management of patients suffering from depression and dementia may be the most promising gift of medical science and technology to humanity. Nonlinear dynamic analysis (NDA) of EEG (electroencephalography) may aid in the differential diagnosis of dementias. However, the methodologies have to be standardised further to make it clinically acceptable universally. ERPs (event related potentials in EEG) can be of great help in diagnosis and also assessing prognosis of dementias. Finally, fusion or hybrid techniques, especially those incorporating fMRI or functional magnetic resonance imaging (along with qEEG or quantitative EEG) can be of immense help in diagnosing, managing and predicting the prognosis of depression and dementia. This book discusses the above issues and offers an important update in the area of depression and dementia. |
Contents
19 | |
DEPRESSION DEMENTIA AND DEXTERITY IN QUEST OF A DENOMINATOR | 53 |
BIOMARKER EPIDEMIOLOGY OF DEPRESSION POPULATION BASED EVIDENCES OF NEUROCHEMICAL AND GENETIC ABNORMALI... | 83 |
SELECTIVE NEURONAL VULNERABILITY BLOODBRAIN BARRIER DISRUPTION AND HEAT SHOCK PROTEIN EXPERSSION IN STRESS ... | 95 |
MULTIPRONGED APPROACH FOR STUDYING LATERALIZATION IN DEPRESSION | 151 |
RECENT ADVANCES IN THE BIOLOGY OF DEPRESSION CLINICAL PERSPECTIVES | 181 |
NONLINEAR DYNAMICAL ANALYSIS ITS APPLICATIONS TO EEG RECORDINGS IN DEMENTIAS | 211 |
EEG IN DEMENTIA REVIEW OF THE PAST VIEW INTO THE FUTURE | 243 |
EVENT REALETD POTENTIALS ERP IN DEMENTIA AND COGNITIVE IMPAIRMENT | 303 |
EPILOGUE | 310 |
INDEX | 320 |
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Common terms and phrases
abnormalities alpha Alzheimer's disease amplitude analysis antidepressants associated asymmetry attractor behavior beta Biological bipolar blood-brain barrier Borod brain function cerebral blood flow changes cholinergic clinical cognitive impairment complex controls correlation dimension cortex cortical decreased delta demented dementia depressed patients diagnostic drugs dysfunction effects elderly Electroencephalogr Clin Neurophysiol electroencephalogram electroencephalography emotional endothelial cell event-related potentials evidence facial factors fractal frequency frontal healthy heat shock heat shock protein heat stress hippocampus HSP expression hyperthermia increased Jelic Journal latency lateralization lesions Lyapunov exponents major depression Mandal measures mental metabolism methods MMSE motoneuronal motor neuroimaging Neurology neuronal neuropsychological Neurosci neurotransmitter nonlinear dynamics normal Parkinson's disease pathology phase space potentials processing Psychiatry qEEG quantitative EEG rats receptor reported response right hemisphere role Sarbadhikari schizophrenia serotonin Sharma H S significant specific spectral spinal cord studies subjects symptoms temporal theta treatment variables vascular visual Westman
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